12 Dec, 2014
Establishment and characterization of a neuronal cell line derived from a 2-cell stage human embryo: clinically tested cell-based therapy for neurological disorders
Geeta Shroff
Regeneration of damaged neurons in neurodegenerative disorders like cerebral palsy and spinal cord injury is a major challenge.
Over 50 publications in international peer reviewed journals
She has published about the unique allogenic stem cell technology, its scientific validations, research papers and studies showing safety and efficacy supported by both documented medical evidence and statistical analysis. She has also authored a chapter in a book.
To describe the morphogenesis of different neuronal cells from the human embryonic stem cell (hESC) line, SCT-N, under in vitro culture conditions.
Human embryonic stem cells are pluri – potent cell lines usually derived from human
Human embryonic stem cells (hESCs) have a role in treating neurological disorders. The
“Human embryonic stem cells (hESCs) are pluripotent cells that have the potential to
“Cerebral palsy (CP) is caused by abnormalities in the developing brain leading to an
Spinal cord injury (SCI) is a devastating disease which impacts the patient physically, psychologically and financially.
Age-related macular degeneration (AMD), a progressive neurodegenerative condition, primarily affects the retinal pigmented epithelium resulting in degeneration of photoreceptors.
Human embryonic stem cell (hESC) therapy is the potential therapeutic option for the treatment of patients with aplastic anemia (AA)
The first human embryonic stem cell (hESC) line was developed in the late nineties. hESCs are capable of proliferating indefinitely and differentiate into all the…
Lyme Disease (LD) is a tick-borne disease caused by Borreliaburgdorferi (Bb) and transmitted in humans by Ixodesscapularis. LD can affect any organ of the body.
The first human embryonic stem cell (hESC) line was developed in the late nineties.
The major complication faced by patients with chronic static spinal cord injury (SCI) is the loss of mobilization.
Stroke or cerebrovascular accident happens when a part of the brain gets poor supply of blood that leads to either hemorrhage or blockage due to…
Human embryonic stem cells (hESCs) have a role in treating neurological disorders. The efficacy and safety of hESC in treating spinal cord injury (SCI) was…
Human embryonic stem cells are pluripotent cell lines usually derived from human blastocysts.
Spinal cord injury (SCI) is a neurological condition which paralyzes the patient below the level of injury and could occur due to damage, infection and…
Down syndrome (DS) is a common chromosomal disorder caused by trisomy of chromosome 21 (HSA21q). Individuals with DS suffer from various congenital and progressive diseases
Friedreich’s ataxia (FRDA) is an autosomal recessive inherited disease that damages the nervous system and impairs muscle coordination.
Background: Low vision is referred to as visual impairment (VI) if it is not cured through surgery, drugs, spectacles or contact lenses.
Parkinson’s disease (PD), a progressive disorder of the central nervous system, affects every 1 in 100 persons, aged around 70 in Europe
Spinal cord injury is a cause of severe disability and mortality. The pharmacological and non-pharmacological methods used, are unable to improve the quality of life…
Purpose—Stem cell therapy is a promising modality for treatment of patients with chronic cerebrovascular accident (CVA) in whom treatment
Emphysema results in narrowing of the small airways due to inhaling of cigarette smoke and other noxious particles.
cerebral palsy (CP), a neurological disorder, has no known cure. The treatments with medicines, surgery and rehabilitation therapies may improve the child’s condition but the…
Treatment options such as corticosteroids, immunoglobulins medicines, blood or platelet transfusions, or splenectomy are used for thrombocytopenia patients
Introduction: Diabetes mellitus (DM), a metabolic disorder, is known to be highly prevalent in people aged 40 – 60 years in developing countries
The expanded disability status scale (EDSS) is a validated and reliable tool to assess the extent of disabilities in patients with multiple sclerosis (MS)
Multiple sclerosis (MS) is a common neurological disease characterized by recurrent relapses within the central nervous system (CNS)
Crohn’s disease is a chronic inflammatory disease of the intestines, mainly the colon and ileum, related with ulcers and fistulae.
Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease in which the myelin sheath of nerve cells is damaged.
The purpose of this study was to evaluate the longitudinal changes in brain perfusion in patients with Lyme disease treated with human embryonic stem cells.
Spinocerebellar ataxias, dominantly inherited ataxias, constitute a large heterogenous group of progressive neurodegenerative disorders that commonly affects the cerebellum and its afferent and efferent pathways.
Spinal cord injury (SCI) is a devastating disorder affecting millions across the world. Still, there is no standard approach for the treatment of SCI.
Duchenne muscular dystrophy (DMD), an X-linked disorder, occurs due to mutation, deletion or duplication of the DMD gene which encodes the protein dystropin.
To describe the morphogenesis of different neuronal cells from the human embryonic stem cell (hESC) line, SCT-N, under in vitro culture conditions.
Brain SPECT is an extremely useful tool in monitoring the treatment response to stem cell therapy in patients of cerebral palsy.
Wound healing occurs by regeneration or repair in which the damaged tissue at the wound site is replaced with fibroblastic mediated scar tissue
To evaluate the safety and efficacy of human embryonic stem cells (hESCs) for the management of type 2 diabetes mellitus (T2DM)
Cerebral Palsy (CP) is a group of permanent neurological disorders which is prevalent in children of neonatal age and is often associated with epilepsy and…
A non-progressive disorder cerebral palsy (CP) occurs as a result of the damage to the brain of a fetus and newborns
The patients admitted to NUTECH Mediworld create a random and unbiased database. Forty-six symptoms assess spinal cord injury (SCI) cases.
To develop a new scoring system, nutech functional scores (NFS) for assessing the patients with spinal cord injury (SCI).
Spinal cord injury (SCI) results in long-lasting Locomotor and sensory neuron degeneration
Background: Autism spectrum disorder is a neurodevelopmental disorder accompanied by weak immune system and neuroinflammation.
Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia. The symptoms of hyperglycemia include polyuria, polydipsia, polyphagia, blurred vision and weight loss.
Multiple sclerosis (MS) is a chronic demyelinating disease with inflammatory neurodegeneration. It is caused by the genesis of an autoimmune response to self-antigens in a…
Glaucoma is a degenerative, optic neuropathy that results in damage to the optic nerve due to increased intraocular pressure (IOP)
Traumatic brain injury (TBI) usually results from a blunt or penetrating force to the head
The present study evaluated the efficacy and safety of human embryonic stem cell (hESC) therapy in patients with CP.
To evaluate the efficacy and safety of hESC therapy on 22 patients with CVA.
Treatment options such as corticosteroids, immunoglobulins medicines, blood or platelet transfusions, or splenectomy are used for thrombocytopenia patients
Parkinson’s disease (PD), a progressive disorder of the central nervous system, affects every 1 in 100 persons, aged around 70 in Europe
The purpose of this study was to evaluate the longitudinal changes in brain perfusion in patients with Lyme disease treated with human embryonic stem cells.
The patients admitted to NUTECH Mediworld create a random and unbiased database. Forty-six symptoms assess spinal cord injury (SCI) cases.
Background: Low vision is referred to as visual impairment (VI) if it is not cured through surgery, drugs, spectacles or contact lenses.
To develop a new scoring system, nutech functional scores (NFS) for assessing the patients with spinal cord injury (SCI).
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